Raúl Rodríguez Berríos

Chemistry Graduate and Undergraduate Program

Assistant Professor of Chemistry
University of Puerto Rico, Rio Piedras Campus (UPR-RP)
Office location: CN:228
Laboratory location: CN-202B
Phone: 787-764-0000 x 88514
email: raulr.rodriguez@upr.edu

Research Interests

  • Chemical education: Organic chemistry and biochemistry
  • Biochemistry research: study the mitochondrial function in different cell lines to evaluate drug candidates
  • Organic synthesis: Synthesis of fullerene derivatives and functionalization of steroid hormones
  • Biological activity evaluation


Dr. Rodriguez laboratory has two areas of research: chemistry education research in organic chemistry (CEROC) and biochemistry and organic chemistry synthesis. The CEROC projects include developing new undergraduate experiments and the integration of technology in undergraduate laboratories for organic chemistry and biochemistry, and the study of the student performance in traditional vs online lectures to improve the BS chemistry curriculum and introduce new elective courses. In the area or organic synthesis, the aims include the synthesis and characterization of fullerene C60 using asymmetric catalysis and cycloaddition reactions and the functionalization of sexual hormones. The new fullerene and steroid derivates will be evaluated in terms of the potential to use as materials and new drugs candidates.


Regiocontrolled ring opening of monoprotected 2,3-epoxy diols using alkynyl aluminum reagents. Synthesis of differentially monoprotected alkynyl triol derivatives. Authors: José A. Prieto, Jaileen Rentas Torres, Raul Rodríguez-Berrios, Synlett, 2014, vol 25, pp 433-437, DOI:10.1055/s-0033-1340332

Stereoselective VO(acac)2 Catalyzed Epoxidation Of Acyclic Homoallylic Diols. Complementary Preparation of C2-Syn-3,4-Epoxy Alcohols. Authors: Raúl R. Rodríguez-Berríos, Gerardo Torres, José A. Prieto, Tetrahedron, 2011, vol 67, pp 830-836, DOI:10.1016/j.tet.2010.11.079

Stereoselective Construction of all-anti Polypropionate Modules: Synthesis of the C5-C10 Fragment of Streptovaricin U. Authors: Wildeliz Torres; Raúl R. Rodríguez; José A. Prieto, The Journal of the Organic Chemistry, 2009, vol 74, pp 2447-2451, DOI: 10.1021/jo8026966