Chemistry Graduate and Undergraduate Professor
e-mail: jose.prieto2@upr.edu.
Office: Facundo Bueso Building, FB-111
Telephone: 787-787-759-6880, Fax 787-759-6885
Laboratory: Facundo Bueso Building, FB-104
Research Interests
-Organic and organometallic synthesis
-Lewis acid catalysis
-new methodologies for the synthesis of biologically active compounds
-chiral synthesis of polypropionates based on oxirane chemistry
Publications
“Stereoselective construction of all-anti polypropionate modules: Synthesis of the C5-C10 fragment of streptovaricin U”, Torres, Wildeliz; Rodriguez, Raul; Prieto, José J. Org. Chem. 2009, 74, 2447–2451. (doi: 10.1021/jo8026966)
“Regioselective Cleavage of 3,4-Epoxy Alcohols with Substituted Alkynylaluminum Reagents: Application to the Stereoselective Synthesis of Polypropionates” Dávila, W.; Torres, W.; Prieto, J. A. Tetrahedron 2007, 67, 8218-8226. (doi:10.1016/j.tet.2007.05.122)
“Highly Regioselective Copper Catalyzed cis- and trans-1-Propenyl Grignard Cleavage of Hindered Epoxides. Application in Propionate Synthesis”, Rodríguez, D.; Mulero, M.; Prieto, J. A.* J. Org. Chem. 2006, 71, 5826-5829. (doi: 10.1021/jo060833t)
“Regioselective Cleavage of cis- and trans-2-Methyl-3,4-Epoxy Alcohols with Diethylpropynyl Aluminum”, Tirado, R.; Torres, G.; Torres, W.; Prieto, J. A.* Tetrahedron Lett. 2005, 46, 797-801. (doi:10.1016/j.tetlet.2004.12.018)
“Microwave-assisted epoxidation of hindered homoallylic alcohols using VO(acac)2: Application to polypropionate synthesis”, Torres, G.; Torres, W.; and Prieto, J. A.* Tetrahedron 2004, 60, 10245-10251. (doi:10.1016/j.tet.2004.08.095)
“Efficient Hydroxyl Inversion in Polypropionates via Cesium Carboxylates”, Arbelo, D. O.; Castro-Rosario, L. and Prieto, J. A.* Synthetic Commun. 2003, 33, 3211-3223. (doi: 10.1081/SCC-120023443)
“Using Molecular Modeling in the in the Organic Chemistry Course for Majors”, Montes, I.; Prieto, J. A.; García, M. The Chemical Educator 2002, 7, 293-296. (doi 10.1333/s00897020593a)
“Cesium propionate as an epoxide cleavage and inversion reagent”, Arbelo, D. O.; and Prieto, J. A. Tetrahedron Lett. 2002, 43, 4111-4114. (doi:10.1016/S0040-4039(02)00739-6)
“Synthesis of Functionalized Enamines from Lithium Alkyl Phenyl Sulfones and N-Carbo-tert-Butoxy Lactams” Arias, L. Arbelo, D. Alzérreca, A. and Prieto, José A. J. Heterocyclic Chem. 2001, 38, 29-33.