Jorge L. Colón Rivera

Chemistry Graduate Program Mentor
e-mail: jorge.colon10@upr.edu
Office Location: Facundo Bueso 109
Office Phone: (787)402-2015

Research Interests
-Nanomaterials
-Electrocatalysis
-Biosensors
-Drug delivery

Research
We focus our research efforts on the use of layered inorganic nanomaterials in applications ranging from artificial photosynthesis and solar fuels, electrocatalysts for the water splitting reaction, amperometric biosensors, vapochromic materials, and drug delivery systems. We make use of X-ray powder diffraction methods, UV-vis spectrophotometry, luminescence spectroscopy and lifetime measurements, X-ray photoelectron, NMR and IR spectroscopies, and electrochemical methods to characterize and study our materials. We are pursuing an artificial photosynthesis project in which excited state electron donors are being intercalated in zirconium phosphate layered materials and reacted with suitable quenchers to provoke long-lived charge separation as a way to mimic the primary processes of photosynthesis and develop cheap, efficient, solar cells. The promise of low-cost and efficient dye-sensitized solar cells based on perovskite materials is impeded by their low stability; zirconium phosphate composites with perovskite might overcome this limitation. Solar catalysts for renewable fuels based on metals and molecular catalysts incorporated in or on zirconium phosphate are being studied through electrocatalytic studies. We focus our research efforts on the use of layered inorganic nanomaterials in applications ranging from artificial photosynthesis and solar fuels, electrocatalysts for the water splitting reaction, amperometric biosensors, vapochromic materials, and drug delivery systems. We make use of X-ray powder diffraction methods, UV-vis spectrophotometry, luminescence spectroscopy and lifetime measurements, X-ray photoelectron, NMR and IR spectroscopies, and electrochemical methods to characterize and study our materials.

Publications
Santiago, M. B.; Daniel, G. A.; David, A.; Casañas, B.; Hernández, G.; Guadalupe, A. R.; Colón, J. L. Effect of enzyme and cofactor immobilization on the response of ethanol amperometric biosensors modified with layered zirconium phosphate. Electroanalysis 2010, 22, 1097-1105. DOI: 10.1002/elan.200900329 First published online 30 Mar 2010.

Martí, A. A.; Colón, J. L. Photophysical characterization of Tris(2-2’-bipyridyl)ruthenium(II) Ion-Exchanged within Zirconium Phosphate. Inorg. Chem. 2010, 49, 7298-7303. http://pubs.acs.org/doi/abs/10.1021/ic902419z Publications Date (Web): July 19, 2010.

Díaz, A.; David, A.; Pérez, R.; González, M. L.; Báez, A.; Wark, S. E.; Zhang, P.; Clearfield, A.; Colón, J. L. Nanoencapsulation of Insulin into Zirconium Phosphate for Oral Delivery Applications. Biomacromolecules 2010, 11, 2465-2470. http://pubs.acs.org/doi/abs/10.1021/bm100659p Publication Date (Web): August 13, 2010.

Rivera, E. J.; Barbosa, C.; Torres, R.; Grove, L.; Taylor, S.; Connick, W. B.; Clearfield, A.; Colón, J. L. Vapochromic and Vapoluminescence Response of Materials based on Platinum(II) Complexes intercalated into Layered Zirconium Phosphate. J. Mater. Chem. 2011, 21, 15899-15902. http://pubs.rsc.org/en/content/articlelanding/2011/jm/c1jm12053k#!divAbstract First published online 7 Sep 2011.

Díaz, A.; Saxena, V.; González, J.; David, A.; Casañas, B.; Batteas, J. D.; Colón, J. L.; Clearfield, A.; Hussain, M. D. Zirconium phosphate nano-platelets: a novel platform for drug delivery in cancer therapy. Chem. Commun. 2012, 48, 1754-1756. http://pubs.rsc.org/en/content/articlelanding/2012/cc/c2cc16218k#!divAbstract First published online 13 Dec 2011.

Santiago-Berríos, M. B.; Declet-Flores, C; David, A.; Borrero, S.; Vélez, M. M.; Díaz-Díaz, A.; Guadalupe, A. R.; Colón, J. L. Direct Intercalation of Bis-2,2’,2”,6-terpyridyl Cobalt (III) into Zirconium Phosphate Layers for Biosensing Applications. Langmuir 2012, 28, 4447-4452. http://pubs.acs.org/doi/abs/10.1021/la2035104 Publication Date (Web): February 8, 2012.

Rivera, E. J.; Barbosa, C.; Torres, R.; Rivera, H.; Fachini, E. R.; Green, T. W.; Connick, W. B.; Colón, J. L. Luminescence Rigidochromism and Redox Chemistry of Pyrazolate-Bridged Binuclear Platinum(II) Diimine Complex Intercalated into Zirconium Phosphate Layers. Inorg. Chem. 2012, 51, 2777-2784. http://pubs.acs.org/doi/abs/10.1021/ic201423q Publication Date (Web): February 16, 2012.

Colón, J. Science for Haiti: A Call for a Response from the International Chemistry Community. Chem. Int. 2012, 34, 10-13.

Díaz, A.; Pérez, R. J.; David, A.; González, M. L.; Báez, A.; Kinnibrugh, T. B.; Zhang, P.; Clearfield, A.; Colón, J. L. Direct Intercalation of Cisplatin into Zirconium Phosphate Nanoplatelets for Potential Cancer Nanotherapy. Nanoscale 2013, 5, 11456-11463. http://pubs.rsc.org/en/content/articlelanding/2013/nr/c3nr02206d#!divAbstract First published online: 30 August 2013. Part of the themed collection: Functional Nanoparticles for Biomedical Applications. http://pubs.rsc.org/en/journals/articlecollectionlanding?sercode=nr&themeid=1f10a761-4f65-425f-8b8c-c29ac839b48a

Colón, J. L.; Casañas, B. Drug Carriers Based on Zirconium Phosphate Nanoparticles. In Tailored Organic-Inorganic Materials, Brunet, E.; Colón, J. L.; Clearfield, A. Eds., Wiley: Hoboken, 2015 pp 395-437. http://onlinelibrary.wiley.com/doi/10.1002/9781118792223.ch10/pdf Published online: 8 May, 2015.

Casañas-Montes, B.; Díaz, A.; Barbosa, C.; Ramos, C.; Collazo, C.; Meléndez, E.; Queffelec, C.; Fayon, F.; Clearfield, A.; Bujoli, B.; Colón, J. L. Molybdocene dichloride intercalation into zirconium phosphate nanoparticles. J. Organomet. Chem. 2015, 791, 34-40. http://www.sciencedirect.com/science/article/pii/S0022328X15300036 Available online: 27 May, 2015.

Colón, J. L. Science for Haiti: International Collaborations to Advance Haitian Science and Science Education Capacity and Innovation. In Jobs, Collaborations, and Women Leaders in the Global Chemistry Enterprise, Chen, H. N.; Wu, M. L.; Miller, B. D. Eds., ACS Symposium Series Vol. 1195, American Chemical Society: Washington, DC, 2015, pp 169-182. Publication Date (Web): September 2, 2015. Doi:10.1021/bk-2015-1195.ch017.

Colón, J. L. Puerto Rico’s Future at Stake. Science 2015, 349, 1145. Publication Date (Web):September 11, 2015. DOI: 10.1126/science.aad3620

González, M. L.; Ortiz, M.; Hernández, C.; Cabán, J.; Rodríguez, A.; Colón, J. L.; Báez, A. Zirconium Phosphate Nanoplatelet Potential for Anticancer Drug Delivery Applications. Journal of Nanoscience and Nanotechnology 2016, 16, 117-129. http://www.ingentaconnect.com/content/asp/jnn/2016/00000016/00000001/art00008?token=00441ae6fdc8c0e2265a666f3a7b6c53407b423b6b634c76763f49266d652fd5dee1 January 2016.

Colón, J. The Solar Army: Harry Gray’s Legacy to the Children of the World. Chem. Int. 2016, 38, 12-15. https://doi.org/10.1515/ci-2016-0606

Bakhmutov, V. I., Kan, Y., Sheikh, J. A., González-Villegas, J., Colón, J. L., and Clearfield, A. Modification and Intercalation of Layered Zirconium Phosphates: A solid state NMR Monitoring. Mag. Reson. Chem. 2017, 55, 648-654. DOI: 10.1002/mrc.4568.

Sánchez, J.; Ramos-Garcés, M. V.; Narkeviciute, I.; Colón, J. L.; Jaramillo, T. F. Transition Metal-Modified Zirconium Phosphate Electrocatalysts for Oxygen Evolution Reaction. Catalysts 2017, 7, 132. http://www.mdpi.com/2073-4344/7/5/132 This article made the cover of that issue of the journal.

González-Villegas, J.; Kan, Y.; Bahkmutov, V.; García-Vargas, A.; Martínez, M.; Colón, J.L.; Clearfield, A. Poly(ethylene glycol)-modified zirconium phosphate nanoplatelets for improved doxorubicin delivery. Inorg. Chim. Acta 2017, 468, 270-279. doi.org/10.1016/j.ica.2017.05.057.

Massol-Deyá, A.; Stephens, J. C.; Colón, J. L. Renewable energy for Puerto Rico. Science 2018, 362, 7. Publication Date (Web): October 5, 2018. DOI: 10.1126/science.aav5576

Ramos-Garcés, M.; Sanchez, J.; Del Toro-Pedrosa, D. E.; Barraza Alvarez, I; Wu, Y; Valle, E.; Villagran, D.; Jaramillo, T. F.; Colón, J. L.Transition metal-modified exfoliated zirconium phosphate as a electrocatalyst for the oxygen-evolution reaction. ACS Appl. Energy Mater. 2019, 2, 3561-3567. DOI: 10.1021/acsaem.9b00299.

Ramos-Garcés, M.; Sanchez, J.; Barraza Alvarez, I; Wu, Y; Villagran, D.; Jaramillo, T. F.; Colón, J. L. Water splitting electrocatalysis within layered inorganic nanomaterials. In Water Splitting, Eyvaz, M. Ed.; Intech Open: London, 2019, in press.