{"id":1965,"date":"2020-04-19T15:30:40","date_gmt":"2020-04-19T15:30:40","guid":{"rendered":"http:\/\/natsci.uprrp.edu\/chemistry\/?page_id=1965"},"modified":"2026-02-24T12:12:31","modified_gmt":"2026-02-24T16:12:31","slug":"marvin-j-bayro","status":"publish","type":"page","link":"https:\/\/natsci.uprrp.edu\/chemistry\/marvin-j-bayro\/","title":{"rendered":"Marvin J. Bayro"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1965\" class=\"elementor elementor-1965\">\n\t\t\t\t<div class=\"elementor-element elementor-element-18772811 e-flex e-con-boxed e-con e-parent\" data-id=\"18772811\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1007b607 elementor-widget elementor-widget-text-editor\" data-id=\"1007b607\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<figure id=\"attachment_1966\" aria-describedby=\"caption-attachment-1966\" style=\"width: 250px\" class=\"wp-caption alignnone\"><a href=\"https:\/\/natsci.uprrp.edu\/chemistry\/wp-content\/uploads\/sites\/3\/2020\/04\/marvinbayro-Marvin-J-Bayro.jpg\"><img fetchpriority=\"high\" decoding=\"async\" class=\"size-full wp-image-1966\" src=\"https:\/\/natsci.uprrp.edu\/chemistry\/wp-content\/uploads\/sites\/3\/2020\/04\/marvinbayro-Marvin-J-Bayro.jpg\" alt=\"imagen profesor Marvin J Bayro\" width=\"250\" height=\"250\" srcset=\"https:\/\/natsci.uprrp.edu\/chemistry\/wp-content\/uploads\/sites\/3\/2020\/04\/marvinbayro-Marvin-J-Bayro.jpg 250w, https:\/\/natsci.uprrp.edu\/chemistry\/wp-content\/uploads\/sites\/3\/2020\/04\/marvinbayro-Marvin-J-Bayro-150x150.jpg 150w\" sizes=\"(max-width: 250px) 100vw, 250px\" \/><\/a><figcaption id=\"caption-attachment-1966\" class=\"wp-caption-text\">Dr. Marvin J. Bayro &#8211; Assistant Professor<\/figcaption><\/figure>\n<h4 class=\"ContentPasted0\"><strong class=\"ContentPasted0\">Chemistry Graduate and Undergraduate Assistant Professor<\/strong><\/h4>\n<p class=\"ContentPasted0\">email: <a class=\"ms-outlook-linkify\" href=\"mailto:marvin.bayro@upr.edu\">marvin.bayro@upr.edu<\/a><br class=\"ContentPasted0\" \/>Office: MSRC 238<br class=\"ContentPasted0\" \/>Laboratory: MSRC 2-31\/32<br class=\"ContentPasted0\" \/>Office phone: 787-523-5326<br class=\"ContentPasted0\" \/>Website:<span class=\"ContentPasted0\">\u00a0<\/span><a id=\"OWAb274e1fa-fb3a-79e5-23ca-a0c44dafa18a\" class=\"OWAAutoLink ContentPasted0\" title=\"Original URL: https:\/\/nmrvin.wordpress.com\/ Click to follow link.\" href=\"https:\/\/nam02.safelinks.protection.outlook.com\/?url=https%3A%2F%2Fnmrvin.wordpress.com%2F&amp;data=05%7C01%7Ccarmen.acosta3%40upr.edu%7C7a6a8d83ae6d4351ac8c08dba8e982e6%7C0dfa5dc0036f461599e494af822f2b84%7C0%7C0%7C638289493097745275%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&amp;sdata=v6on3BKOpCjoqLV9ef5XvY%2FJxIZ1TbTWVOkeje5AFrY%3D&amp;reserved=0\" data-loopstyle=\"linkonly\">https:\/\/nmrvin.wordpress.com\/<\/a><br class=\"ContentPasted0\" \/>Social media:<span class=\"ContentPasted0\">\u00a0<\/span><a id=\"OWAd5afd610-571d-63b2-3447-48cd8aa12533\" class=\"OWAAutoLink ContentPasted0\" title=\"Original URL: https:\/\/instagram.com\/proteinnmrgroup?r=nametag Click to follow link.\" href=\"https:\/\/nam02.safelinks.protection.outlook.com\/?url=https%3A%2F%2Finstagram.com%2Fproteinnmrgroup%3Fr%3Dnametag&amp;data=05%7C01%7Ccarmen.acosta3%40upr.edu%7C7a6a8d83ae6d4351ac8c08dba8e982e6%7C0dfa5dc0036f461599e494af822f2b84%7C0%7C0%7C638289493097745275%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&amp;sdata=13SB1%2Bj2wFWfVd%2FmOasZ1arOTc%2B30y1qjViBVFT8wdQ%3D&amp;reserved=0\" data-loopstyle=\"linkonly\">proteinnmrgroup<\/a><\/p>\n<p><!-- \/wp:paragraph --><!-- wp:paragraph --><\/p>\n<p>\u00a0<\/p>\n<h4><strong class=\"ContentPasted0\">Research Interests<\/strong><\/h4>\n<p><!-- \/wp:paragraph --><!-- wp:list {\"className\":\"ContentPasted0\"} --><\/p>\n<ul class=\"wp-block-list ContentPasted0\">\n<li style=\"list-style-type: none\">\n<ul class=\"wp-block-list ContentPasted0\"><!-- wp:list-item --><\/ul>\n<\/li>\n<\/ul>\n<ul class=\"wp-block-list ContentPasted0\">\n<li style=\"list-style-type: none\">\n<ul class=\"wp-block-list ContentPasted0\">\n<li>NMR spectroscopy<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><!-- \/wp:list-item --><!-- wp:list-item --><\/p>\n<ul class=\"wp-block-list ContentPasted0\">\n<li style=\"list-style-type: none\">\n<ul class=\"wp-block-list ContentPasted0\">\n<li>Protein structure and dynamics<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><!-- \/wp:list-item --><!-- wp:list-item --><\/p>\n<ul class=\"wp-block-list ContentPasted0\">\n<li style=\"list-style-type: none\">\n<ul class=\"wp-block-list ContentPasted0\">\n<li>Biomolecular solid-state NMR<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><!-- \/wp:list-item --><!-- wp:list-item --><\/p>\n<ul class=\"wp-block-list ContentPasted0\">\n<li style=\"list-style-type: none\">\n<ul class=\"wp-block-list ContentPasted0\">\n<li>HIV structure and assembly<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><!-- \/wp:list-item --><!-- wp:list-item --><\/p>\n<ul class=\"wp-block-list ContentPasted0\">\n<li style=\"list-style-type: none\">\n<ul class=\"wp-block-list ContentPasted0\">\n<li>Nanoparticles and bionanomaterials<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><!-- \/wp:list-item --><!-- wp:list-item --><\/p>\n<ul class=\"wp-block-list ContentPasted0\">\n<li style=\"list-style-type: none\">\n<ul class=\"wp-block-list ContentPasted0\">\n<li>Protein-drug interactions<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><!-- \/wp:list-item --><\/p>\n<p><!-- \/wp:list --><!-- wp:paragraph {\"className\":\"ContentPasted0\"} --><\/p>\n<h4 class=\"ContentPasted0\"><strong class=\"ContentPasted0\">Research<\/strong><\/h4>\n<p><!-- \/wp:paragraph --><!-- wp:paragraph {\"className\":\"ContentPasted0\"} --><\/p>\n<p class=\"ContentPasted0\">Our group studies\u00a0biomolecular assemblies and interactions using solution and solid-state NMR spectroscopy. We are interested in HIV proteins and their structural mechanisms\u00a0in virion formation, maturation, and their inhibition. In addition, we implement state-of-the-art spectroscopic methods to understand protein-protein and protein-drug interactions related to human disease and therapeutic strategies.<\/p>\n<p><!-- \/wp:paragraph --><!-- wp:paragraph {\"className\":\"ContentPasted0\"} --><\/p>\n<p class=\"ContentPasted0\"><span class=\"ContentPasted1\">We also develop NMR-based techniques to characterize polymer assemblies designed for carbon capture and to elucidate biomineralization mechanisms. This biomimetic nanomaterials project is a DOE-funded collaboration with Pacific Northwest National Laboratory (<a id=\"LPNoLPOWALinkPreview\" title=\"Original URL: https:\/\/www.pnnl.gov\/publications\/mimicking-nature-store-carbon-dioxide-minerals Click to follow link.\" href=\"https:\/\/nam02.safelinks.protection.outlook.com\/?url=https%3A%2F%2Fwww.pnnl.gov%2Fpublications%2Fmimicking-nature-store-carbon-dioxide-minerals&amp;data=05%7C01%7Ccarmen.acosta3%40upr.edu%7C7a6a8d83ae6d4351ac8c08dba8e982e6%7C0dfa5dc0036f461599e494af822f2b84%7C0%7C0%7C638289493097745275%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&amp;sdata=ey0tAL%2FY8Xwmcuzm0kuuhGr94aatAr8KskqIgStJtKs%3D&amp;reserved=0\">https:\/\/www.pnnl.gov\/publications\/mimicking-nature-store-carbon-dioxide-minerals<\/a>)<\/span><\/p>\n<p><!-- \/wp:paragraph --><!-- wp:paragraph --><\/p>\n<h4><strong class=\"ContentPasted0\">Publications<\/strong><\/h4>\n<p><!-- \/wp:paragraph --><!-- wp:paragraph {\"className\":\"ContentPasted0\"} --><\/p>\n<p class=\"ContentPasted0\">Cruz-Collazo A, Ruiz-Calderon JF, Picon H, Borrero-Garcia LD, Lopez I, Castillo-Pichardo L, Del Mar Maldonado M, Duconge J, Medina JI, Bayro MJ, Hern\u00e1ndez-O\u2019Farrill E, Vlaar CP, Dharmawardhane S. (2021) \u201cEfficacy of Rac and Cdc42 Inhibitor MBQ-167 in Triple-negative Breast Cancer.\u201d Mol Cancer Ther. 20, 2420-2432. PMCID: PMC8643341.<\/p>\n<p><!-- \/wp:paragraph --><!-- wp:paragraph {\"className\":\"ContentPasted0\"} --><\/p>\n<p class=\"ContentPasted0\">Purslow JA, Khatiwada B, Bayro MJ, Venditti V. \u201cNMR Methods for Structural Characterization of Protein-Protein Complexes.\u201d Front Mol Biosci (2020) 7, 9.<\/p>\n<p><!-- \/wp:paragraph --><!-- wp:paragraph {\"className\":\"ContentPasted0\"} --><\/p>\n<p class=\"ContentPasted0\">Vega-Figueroa K, Santill\u00e1n J, Ort\u00edz-G\u00f3mez V, Ortiz-Quiles E, Qui\u00f1ones-Col\u00f3n BA, Castilla- Casadiego DA; Almodovar J, Bayro MJ, Rodr\u00edguez-Mart\u00ednez JA, Nicolau E. \u201cAptamer-based Impedimetric Assay of Arsenite in Water: Interfacial Properties and Performance.\u201d ACS Omega (2018) 3, 1437-1444.<\/p>\n<p><!-- \/wp:paragraph --><!-- wp:paragraph {\"className\":\"ContentPasted0\"} --><\/p>\n<p class=\"ContentPasted0\">Bayro MJ, Ganser-Pornillos B, Yeager M, Tycko R. \u201cHelical conformation in the CA-SP1 junctions of the immature HIV-1 lattice determined from solid-state NMR of virus-like particles.\u201d J Am Chem Soc (2016) 138, 12029-12032.<\/p>\n<p><!-- \/wp:paragraph --><!-- wp:paragraph {\"className\":\"ContentPasted0\"} --><\/p>\n<p class=\"ContentPasted0\">Bayro MJ, Tycko R. \u201cStructure of the dimerization interface in the mature HIV-1 capsid protein lattice from solid state NMR of tubular assemblies.\u201d J Am Chem Soc (2016) 138, 8538- 8546. Featured in JACS Highlights.<\/p>\n<p><!-- \/wp:paragraph --><!-- wp:paragraph {\"className\":\"ContentPasted0\"} --><\/p>\n<p class=\"ContentPasted0\">Lu JX, Bayro MJ, Tycko R. \u201cMajor variations in HIV-1 capsid assembly morphologies involve minor variations in molecular structures of structurally ordered protein segments\u201d J Biol Chem (2016) 291, 13098-13112.<\/p>\n<p><!-- \/wp:paragraph --><!-- wp:paragraph {\"className\":\"ContentPasted0\"} --><\/p>\n<p class=\"ContentPasted0\">Bayro MJ, Chen B, Yau WM, Tycko R. \u201cStructural variations accompanying tubular assembly of the HIV-1 capsid protein.\u201d J Mol Biol (2014) 426, 1109-1127.<\/p>\n<p><!-- \/wp:paragraph --><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Chemistry Graduate and Undergraduate Assistant Professor email: marvin.bayro@upr.eduOffice: MSRC 238Laboratory: MSRC 2-31\/32Office phone: 787-523-5326Website:\u00a0https:\/\/nmrvin.wordpress.com\/Social media:\u00a0proteinnmrgroup \u00a0 Research Interests NMR spectroscopy Protein structure and dynamics Biomolecular solid-state NMR HIV structure and assembly Nanoparticles and bionanomaterials Protein-drug interactions Research Our group studies\u00a0biomolecular assemblies and interactions using solution and solid-state NMR spectroscopy. We &hellip; <\/p>\n","protected":false},"author":23,"featured_media":1966,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1965","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/natsci.uprrp.edu\/chemistry\/wp-json\/wp\/v2\/pages\/1965","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/natsci.uprrp.edu\/chemistry\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/natsci.uprrp.edu\/chemistry\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/natsci.uprrp.edu\/chemistry\/wp-json\/wp\/v2\/users\/23"}],"replies":[{"embeddable":true,"href":"https:\/\/natsci.uprrp.edu\/chemistry\/wp-json\/wp\/v2\/comments?post=1965"}],"version-history":[{"count":18,"href":"https:\/\/natsci.uprrp.edu\/chemistry\/wp-json\/wp\/v2\/pages\/1965\/revisions"}],"predecessor-version":[{"id":3822,"href":"https:\/\/natsci.uprrp.edu\/chemistry\/wp-json\/wp\/v2\/pages\/1965\/revisions\/3822"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/natsci.uprrp.edu\/chemistry\/wp-json\/wp\/v2\/media\/1966"}],"wp:attachment":[{"href":"https:\/\/natsci.uprrp.edu\/chemistry\/wp-json\/wp\/v2\/media?parent=1965"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}