{"id":1959,"date":"2020-05-07T05:15:13","date_gmt":"2020-05-07T05:15:13","guid":{"rendered":"http:\/\/natsci.uprrp.edu\/chemistry\/?page_id=1959"},"modified":"2020-06-15T19:49:23","modified_gmt":"2020-06-15T19:49:23","slug":"vilmali-lopez-mejias","status":"publish","type":"page","link":"https:\/\/natsci.uprrp.edu\/chemistry\/vilmali-lopez-mejias\/","title":{"rendered":"Vilmal\u00ed L\u00f3pez Mej\u00edas"},"content":{"rendered":"

\"\"<\/a><\/p>\n

Chemistry Graduate and Undergraduate Program. <\/strong><\/p>\n

e-mail: vilmali.lopez@upr.edu
\nOffice: Molecular Sciences Research Center Office #247
\nOffice Phone: 787-523-5303
\nLab Phone: 787-764-0000 ext. 88553
\nUPR Address: Molecular Sciences Research Center (UPR’s MSRC) 1390 Ponce De Le\u00f3n Ave. San Juan, Puerto Rico 00926
\nHomepage: https:\/\/cdiupr.weebly.com<\/a><\/p>\n

Social Networks<\/strong>
\nFacebook Group Website: https:\/\/www.facebook.com\/LopezStelzerLabs\/<\/a>
\nFacebook Outreach Website: https:\/\/www.facebook.com\/CreaCienciaPR\/<\/a><\/p>\n

Research Interests<\/strong>
\n-materials science
\n-pharmaceutical sciences
\n-polymer science
\n-analytical chemistry
\n-polymorphism<\/p>\n

Research<\/strong>
\nOur laboratory, the Crystallization Design Institute, provides expertise-based molecular and engineering solutions for materials characterization, solid form discovery & design, and crystallization process development to the academic and industrial sector. We aim to understand how molecular crystals (salt, co-crystals, polymorphs, etc.) form so that we can control and apply these crystallizations to better every day products (pharmaceutical and insecticide formulations, electronic and energetic materials, etc.) and processes (continuous pharmaceutical manufacturing).<\/p>\n

1. L\u00f3pez-Mej\u00edas, V.; Kampf, J.W.; Matzger, A.J. Polymer-Induced Heteronucleation of Tolfenamic Acid: Structural Investigation of a Pentamorph, J. Am. Chem. Soc., 2009, 131, 4554 -4555.<\/p>\n

2. McClelland, A.A.; L\u00f3pez-Mej\u00edas, V.; Matzger, A.J.; Chen, Z. Peering at a Buried Polymer-Crystal Interface: Probing Heterogeneous Nucleation by Sum Frequency Generation Vibrational Spectroscopy, Langmuir, 2011, 27, 2162- 2165.<\/p>\n

3. L\u00f3pez-Mej\u00edas, V.; Knight, J.L.; Matzger, A.J.; Brooks III C.L. On the Mechanism of Polymorph Selection by Polymer Heteronuclei, Langmuir, 2011, 27, 7575-7579.<\/p>\n

4. L\u00f3pez-Mej\u00edas, V.; Kampf, J.W.; Matzger, A.J. Nonamorphism in Flufenamic acid and a New Record for a Polymorphic Compound with Solved Structures, J. Am. Chem. Soc., 2012, 134, 9872-9875.<\/p>\n

5. L\u00f3pez-Mej\u00edas, V.; Myerson, A.S.; Trout, B.L. Geometric Design of Heterogeneous Nucleation Sites on Biocompatible Surfaces, Cryst. Growth & Des., 2013, 13, 3835-3841.<\/p>\n

6. Curcio, E.; L\u00f3pez-Mej\u00edas, V.; Di Profio, G.; Fontananovam E.; Drioli, E.; Trout, B.L.; Myerson, A.S.; Regulating Nucleation Kinetics Through Molecular Interactions at the Polymer-Solute Interface, Cryst. Growth & Des., 2014, 14, 678-686.<\/p>\n

7. L\u00f3pez-Mej\u00edas, V.; Eral, H.B.; Doyle, P.S.; Myerson, A.S.; Trout, B.L. Towards Control of Nucleation and Encapsulation with Alginate Hydrogels: A Biocompatible Vehicle for Hydrophilic and Hydrophobic Drugs, Cryst. Growth &Des., 2014, 14, 2073-2082.<\/p>\n

8. L\u00f3pez-Mej\u00edas, V.; Matzger, A.J., Structure-Polymorphism Study of Fenamates: Toward Developing an Understanding of the Polymorphophore, Cryst. Growth & Des., 2015, 15, 3955-3962.<\/p>\n

9. Hern\u00e1ndez Espinell, J. R.; L\u00f3pez-Mej\u00edas, V.; Stelzer T. Revealing Polymorphic Phase Transformations in Polymerbased Hot-Melt Extrusion Processes Cryst. Growth Des., 2018, 18 (4), 1995\u20132002.<\/p>\n

10. Zorrilla-Veloz, R. I.; Stelzer, T.; L\u00f3pez-Mej\u00edas, V. Measurement and Correlation of the Solubility of 5-Fluorouracil in Pure and Binary Solvents. J. Chem. Eng. Data 2018, 63 (10), 3809\u20133817. https:\/\/doi.org\/10.1021\/acs.jced.8b00425.<\/a><\/p>\n

11. George De la Rosa, M. V.; Santiago, R.; Malav\u00e9 Romero, J.; Duconge, J.; Monbaliu, J.-C.; L\u00f3pez-Mej\u00edas, V.; Stelzer, T. Solubility Determination and Correlation of Warfarin Sodium 2-Propanol Solvate in Pure, Binary, and Ternary Solvent Mixtures. J. Chem. Eng. Data 2019. 64 (4), 1399-1413.<\/p>\n

12. V\u00e1zquez Marrero, V. R.; Pi\u00f1ero Berr\u00edos, C.; De Dios Rodr\u00edguez, L.;
\nStelzer, T.; L\u00f3pez-Mej\u00edas, V. In the Context of Polymorphism: Accurate Measurement, and Validation of Solubility Data, Cryst. Growth Des. 2019, 19, 4101\u22124108. DOI: 10.1021\/acs.cgd.9b00529<\/p>\n","protected":false},"excerpt":{"rendered":"

Chemistry Graduate and Undergraduate Program. e-mail: vilmali.lopez@upr.edu Office: Molecular Sciences Research Center Office #247 Office Phone: 787-523-5303 Lab Phone: 787-764-0000 ext. 88553 UPR Address: Molecular Sciences Research Center (UPR’s MSRC) 1390 Ponce De Le\u00f3n Ave. San Juan, Puerto Rico 00926 Homepage: https:\/\/cdiupr.weebly.com Social Networks Facebook Group Website: https:\/\/www.facebook.com\/LopezStelzerLabs\/ Facebook Outreach … <\/p>\n","protected":false},"author":23,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1959","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/natsci.uprrp.edu\/chemistry\/wp-json\/wp\/v2\/pages\/1959","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/natsci.uprrp.edu\/chemistry\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/natsci.uprrp.edu\/chemistry\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/natsci.uprrp.edu\/chemistry\/wp-json\/wp\/v2\/users\/23"}],"replies":[{"embeddable":true,"href":"https:\/\/natsci.uprrp.edu\/chemistry\/wp-json\/wp\/v2\/comments?post=1959"}],"version-history":[{"count":4,"href":"https:\/\/natsci.uprrp.edu\/chemistry\/wp-json\/wp\/v2\/pages\/1959\/revisions"}],"predecessor-version":[{"id":2202,"href":"https:\/\/natsci.uprrp.edu\/chemistry\/wp-json\/wp\/v2\/pages\/1959\/revisions\/2202"}],"wp:attachment":[{"href":"https:\/\/natsci.uprrp.edu\/chemistry\/wp-json\/wp\/v2\/media?parent=1959"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}