{"id":9143,"date":"2022-01-24T16:35:27","date_gmt":"2022-01-24T16:35:27","guid":{"rendered":"https:\/\/natsci.uprrp.edu\/cahreus\/?page_id=9143"},"modified":"2022-02-09T20:32:22","modified_gmt":"2022-02-09T20:32:22","slug":"kai-griebenow-ph-d","status":"publish","type":"page","link":"https:\/\/natsci.uprrp.edu\/cahreus\/equipo\/kai-griebenow-ph-d\/","title":{"rendered":"Kai Griebenow, Ph.D."},"content":{"rendered":"\t\t
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Investigador: <\/strong>Dr. Kai H. Griebenow<\/span><\/h2>

El Dr. Kai H. Griebenow es natural de Jever, Friesland (Frisia), Germany. El Dr. Griebenow finaliz\u00f3 en\u00a0 1989 su bachillerato en Biolog\u00eda en la Universidad de Marburg y completo su Ph.D. en 1992 del Instituto Max-Planck de Qu\u00edmica de la Radiaci\u00f3n y la Universidad de D\u00fcsseldorf por su trabajo en la organizaci\u00f3n de pigmentos en la bacteria verde flexible Chloroflexus aurantiacus<\/em>, por este trabajo recibi\u00f3 la Medalla Otto-Hahn y se uni\u00f3 al Instituto de Tecnolog\u00eda de Massachusetts (MIT) como becario postdoctoral en 1993\u00a0 donde estudio la Mutag\u00e9nesis Combinatoria, Bibliotecas Gen\u00e9ticas y en esta misma instituci\u00f3n de 1994-1996 se vincul\u00f3 como Asociado Postdoctoral y estudi\u00f3 la estructura y estabilidad de prote\u00ednas. El Dr. Griebenow ha recibido financiaci\u00f3n durante los \u00faltimos 20 a\u00f1os del National Institutes of Health (NIH), el Departamento de Defensa de Estados Unidos, el Departamento de Educaci\u00f3n de Estados Unidos., La Fundaci\u00f3n Nacional de Ciencias\u200b (NSF) de Estados Unidos y de la Administraci\u00f3n Nacional de Aeron\u00e1utica y el Espacio (NASA). El Dr. Griebenow ha ense\u00f1ado algunos cursos que incluyen Bioqu\u00edmica, Bioqu\u00edmica Avanzada, T\u00f3picos Especiales en Estructura de Prote\u00ednas, Formulaci\u00f3n y Entrega de Prote\u00ednas, Qu\u00edmica General y Laboratorio de Qu\u00edmica General. Actualmente, el Dr. Griebenow es profesor e investigador del Departamento de Qu\u00edmica de la Universidad de Puerto Rico del Recinto de Rio Piedras y entre sus intereses de investigaci\u00f3n se encuentra la glicosilaci\u00f3n qu\u00edmica de prote\u00ednas y efecto sobre la estabilidad; din\u00e1mica, estructura y funci\u00f3n de las prote\u00ednas; enzimolog\u00eda no acuosa, sensores amperom\u00e9tricos nanoestructurados basados en enzimas, entrega dirigida de prote\u00ednas farmac\u00e9uticas a partir de nanopart\u00edculas, fotos\u00edntesis de algas tropicales, biodiesel y biocombustibles; y educaci\u00f3n qu\u00edmica.\u00a0<\/p>

Researcher: <\/strong>Dr. Kai H. Griebenow<\/span><\/h2>

Dr. Kai H. Griebenow is native of Jever, Friesland (Frisia), Germany. Dr. Griebenow completed his bachelor’s degree in Biology Diploma at the University of Marburg in 1989 and completed his Ph.D. in 1992 from the Max-Planck Institute for Radiation Chemistry and the University of D\u00fcsseldorf for work on the pigments organization in the green flexible bacterium Chloroflexus aurantiacus<\/em>, for this work he received the Otto-Hahn Medal and joined the Massachusetts Institute of Technology (MIT) as a postdoctoral fellow in 1993 where he studied Combinatorial Mutagenesis, Genetic Libraries and in this same institution from 1994-1996 he was linked as a Postdoctoral Associate and studied the Protein Structure and Stability. Dr. Griebenow has received funding over the past 20 years from the National Institutes of Health (NIH), the US Department of Defense, the US Department of Education, the US National Science Foundation (NSF), and of the National Aeronautics and Space Administration (NASA). Dr. Griebenow has taught a number of courses including Biochemistry, Advanced Biochemistry, Special Topics in Protein Structure, Protein Formulation and Delivery, General Chemistry, and General Chemistry Laboratory. Currently, Dr. Griebenow is a professor and researcher at the Department of Chemistry of the University of Puerto Rico Rio Piedras Campus, and among his research interests are the chemical protein glycosylation and its effect on protein stability, dynamics, structure, and function; non-aqueous enzymology, nano-structured enzyme-based amperometric sensors, targeted delivery of pharmaceutical proteins from nanoparticles, photosynthesis of tropical algae, biodiesel and biofuels; and chemical education.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Informaci\u00f3n<\/span><\/h2>

Correo: <\/strong>kai.griebenow@upr.edu<\/a><\/span><\/p>

Expertise:<\/strong> Bioqu\u00edmica<\/p>

Oficina: <\/strong>Facundo Bueso FB-141\u00a0<\/p>

Tel\u00e9fono de Oficina: <\/strong>N\/A<\/p>

Tel\u00e9fono de Laboratorio: <\/strong>N\/A<\/p>

Horas de Oficina: <\/strong>Por acuerdo<\/p>

Redes sociales:<\/strong> Ninguna<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Publicaciones<\/strong><\/span><\/h2>

Irivette Dominguez-Martinez I, Joaquin-Ovalle F, Ferrer-Acosta Y, Griebenow KH<\/strong> (2022) Folate-decorated cross-linked cytochrome c nanoparticles for active targeting of non-small cell lung carcinoma (NSCLC), Pharmaceutics, in press.<\/p>

Delinois LJ, De Leo\u0301n-Ve\u0301lez O, Benjami\u0301n-Rivera JA, Va\u0301zquez-Medina A, Velez-Cabrera A, Marrero-Sa\u0301nchez A, Maser-Figueroa A, Nieves-Escobar C, Alfonso-Cano D, Caraballo-Rodri\u0301guez D, Grajales-Avile\u0301s G, Rodriguez-Ortiz J, Santiago-Paga\u0301n J, Acosta-Mercado J, Gonza\u0301lez-Gonza\u0301lez K, Ferna\u0301ndez-Adorno K, Santiago-Paga\u0301n L, Nieves-Santiago M, Delgado-Vergara R, A\u0301lvarez-Carrillo V, Torres-A\u0301vila X, I. Miranda Me\u0301ndez GI, Griebenow K<\/strong>, Tinoco AD (2021) Cytochrome c: Using biological insight to engineer an optimized anticancer biodrug, Inorganics 9 (11), 83<\/p>

Torres-Martinez Z, Delgado Y, Ferrer-Acosta Y, Suarez-Arroyo IJ, Joaquin-Ovalle FM, Delinois LJ, Griebenow K<\/strong> (2021) Cancer drug resistance: Key genes and drug delivery systems to improve the effectiveness of chemotherapy. Cancer Drug Resistance 4 (1), 163-191.<\/p>

Delinois LJ, Peon H, Villalobos-Santos JC, Ramirez-Paz J, Miller J, Griebenow KH<\/strong>, Tinoco AD (2020) A cytochrome c-chlorotoxin hybrid protein as a possible antiglioma drug. ChemMedChem 15 (22), 2185-2192<\/p>

Barcelo-Bovea V, Dominguez-Martinez I, Joaquin-Ovalle F, Amador LA, Castro-Rivera E, Medina-Alvarez K, McGoron A, Griebenow K<\/strong>, Ferrer-Acosta Y (2020) Optimization and Characterization of Protein Nanoparticles for the Targeted and Smart Delivery of Cytochrome c to Non-Small Cell Lung Carcinoma, Cancers 12, 1215; doi:10.3390\/cancers12051215.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Investigador: Dr. Kai H. Griebenow El Dr. Kai H. Griebenow es natural de Jever, Friesland (Frisia), Germany. El Dr. Griebenow finaliz\u00f3 en\u00a0 1989 su bachillerato en Biolog\u00eda en la Universidad de Marburg y completo su Ph.D. en 1992 del Instituto … <\/p>\n","protected":false},"author":41,"featured_media":0,"parent":9063,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"class_list":["post-9143","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/natsci.uprrp.edu\/cahreus\/wp-json\/wp\/v2\/pages\/9143","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/natsci.uprrp.edu\/cahreus\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/natsci.uprrp.edu\/cahreus\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/natsci.uprrp.edu\/cahreus\/wp-json\/wp\/v2\/users\/41"}],"replies":[{"embeddable":true,"href":"https:\/\/natsci.uprrp.edu\/cahreus\/wp-json\/wp\/v2\/comments?post=9143"}],"version-history":[{"count":10,"href":"https:\/\/natsci.uprrp.edu\/cahreus\/wp-json\/wp\/v2\/pages\/9143\/revisions"}],"predecessor-version":[{"id":9736,"href":"https:\/\/natsci.uprrp.edu\/cahreus\/wp-json\/wp\/v2\/pages\/9143\/revisions\/9736"}],"up":[{"embeddable":true,"href":"https:\/\/natsci.uprrp.edu\/cahreus\/wp-json\/wp\/v2\/pages\/9063"}],"wp:attachment":[{"href":"https:\/\/natsci.uprrp.edu\/cahreus\/wp-json\/wp\/v2\/media?parent=9143"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}